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Principles and Methods in Receptor Binding - Semantic Scholar

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The following DOST-PNRI developed technologies are now ready for licensing and adoption by any individual or corporation wanting to commercialize the technology:. Joseph G. Anthony C.

Janice S. William F. Michael E. Orio Ciferri. Lucien LeDoux. Patrick Luckett. Thomas Caskey.

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Franco Fraschini. Home Contact us Help Free delivery worldwide. Free delivery worldwide. Bestselling Series. Harry Potter. Popular Features. New Releases. Description One of the major advances in the understanding of the mechanism of action of hormones, neurotransmitters and drugs had arisen from the hypothesis that the physiological or pharmacological responses are trig- gered by their interaction with specific cell compo- nents, termed receptors.

Ligands & receptors

However, the presence of receptors has been inferred from indirect data, and only recently has it been possible to study the kinetics of the interaction between drug and receptors directly, through the so called "binding technique. In the chapters of this book, special interest is devoted to the analysis of the simplest models for the interaction of receptors with their ligands either hormones or neurotransmitters or drugs.

The graphical techniques used to analyze the data from binding exper iments are extensively discussed, together with the statistics that have to be used in binding analysis. Moreover, the basic concepts to analyze binding data using a personal computer are presented.